Uganda has been central to CNIS’s history since 1996, when it helped establish the Injury Control Center, trauma register, and the Kampala Trauma Score. Over decades, CNIS has trained thousands of health workers in surgical, obstetric, and trauma care across Kampala, Mbarara, Gulu, and Soroti. During the northern conflict, tens of thousands of children received life-skills and conflict resolution training. Skills labs were set up in Kampala and Mbarara, while the pandemic prompted important studies on clinical guideline use. With Northern Ontario School of Medicine, CNIS launched digital orthopedic training in Mbarara, alongside Trauma Team Training for health workers in Kisoro. CNIS also has a long-standing hernia repair training program in the country, which it plans to revitalize in digital format by 2026. This strong blend of research, teaching, and innovation highlights Uganda as a focal point for CNIS’s ongoing work in sustainable, digitally enabled surgical education.